BaroFold applies its Pressure Enabled Protein Manufacturing (PreEMT™) technology to improve the tolerability, efficacy and safety of a wide variety of protein therapeutics for bio-pharmaceutical companies, research institutions, and government agencies. PreEMT employs high pressure to disaggregate and refold proteins, which may have a significant impact on the quality of these biotherapeutics by improving their activity, homogeneity and safety. BaroFold also helps companies create novel protein therapeutics, accelerate therapeutic protein development, manufacture follow-on biologics and enable life-cycle management of protein therapeutics.

BaroFold was founded in 2009 by Dr. Matt Seefeldt and Matt Brewer through the acquisitions of a new company and is based on the patented PreEMT technology invented at the University of Colorado in the laboratories of Dr. Ted Randolph and Dr. John Carpenter.  The Company is located at the Fitzsimons Bioscience Park in Aurora, CO and enjoys ample access to talented researchers within the biotech corridor between Denver and Boulder.  Our facility houses state of the art high pressure equipment that can accommodate research studies from proof-of-concept through 10L non-GMP material generation.